Expression of Proliferating Cell Nuclear Antigen (PCNA) in Human Parathyroid Adenoma.
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چکیده
منابع مشابه
Proliferating cell nuclear antigen (PCNA) expression in pituitary adenomas: relationship to the endocrine phenotype of adenoma.
The expression of proliferating cell nuclear antigen (PCNA) correlates to cell proliferation and for this reason it is commonly considered as one of proliferation markers. Since proliferation rate is an important factor determining the tumor aggressiveness, the evaluation of PCNA index (the percentage of PCNA-immunopositive nuclei in the investigated tumor sample) is suggested as useful in pred...
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Proliferating cell nuclear antigen (PCNA) is an auxiliary protein of DNA • @polymerase-• Ý • @ that • @is • @ synthesized • @ during • @ the • @ late • @G1 • @ phase through the S phase of cell proliferation. The expression of PCNA correlates strongly with cell proliferation. In the present study, employing NC-012, which is an anti-human PCNA monoclonal antibody, we performed immunohistochemica...
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Proliferating cell nuclear antigen (PCNA) was originally characterised as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the eukaryotic chromosomal DNA replisome. Subsequent studies, however, have revealed its striking ability to interact with multiple partners, which are involved in several metabolic pathways, including Okazaki fragment processing, DNA rep...
متن کاملComparison of the Expression Level of P53 and Proliferating Cell Nuclear Antigen (PCNA) Genes in the Inflamed and Non-Inflamed Dentigerous Cysts
Background & Aims: The role of P53 and proliferating cell nuclear antigen (PCNA) genes in inflamed and non-inflamed odontogenic cysts is related to cell proliferation but it is unclear. The aim of this study was immunohistochemical evaluation of P53 and PCNA expression in inflamed and non-inflamed dentigerous cysts Methods: In the present study, 23 dentigerous cysts (12 inflamed and 11 non-infl...
متن کاملExpression of proliferating cell nuclear antigen(PCNA) in biopsy and autopsy specimens of gastric carcinoma.
UNLABELLED Although proliferating cell nuclear antigen (PCNA) is known to be an indicator of malignant potential in tumors, the biological and clinicopathological significance of PCNA in tumor tissue is controversial. METHODS Immunohistochemical expression of PCNA was examined in 58 gastric carcinoma tissues obtained at autopsy to test the clinicopathological significance. In addition, in 24 ...
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ژورنال
عنوان ژورنال: ACTA HISTOCHEMICA ET CYTOCHEMICA
سال: 1993
ISSN: 0044-5991,1347-5800
DOI: 10.1267/ahc.26.391